synthesis of some fluorocarbons. It is used as a metal degreasing and dry-cleaning solvent, and to make other organic chemicals. 1,1,1-trichloroethane. Experimental data collected in human subjects indicate that absorption of 1,1,1-trichloroethane is nearly complete following a single breath exposure, and that a steady-state lung retention of 25-30% in humans is achieved within 1-3 hours of continuous exposure. CAS: 71-55-6 . Acute What is 1,1,1-TCA and how is it used? Sections I (Health Hazard Assessments for Noncarcinogenic Effects… Health Based Guidance for Water Health Risk Assessment Unit, Environmental Health Division 651-201-4899 . Environmental Forensics. 1,1,1-TCA is a colorless liquid that evaporates quickly at room temperature. It can react with sodium hydroxide. 1,2-Dichloroethylene, 1,1,1,2- tetrachloroethane, and 1,1- dichloroethane are used primarily as solvents in cleaning, degreasing, and extracting processes (#Simon, 2005). Acute Non -Cancer Health Risk Limit (nHRL. 18 1,1,1-TRICHLOROETHANE decomposes in the presence of chemically active metals. Adopted as Rule: August 2018 . 1960 – 1980 Metal degreasing use peaked in 1970 ... health effects in a population will occur as a result of exposure to chemicals in the environment. It may cause health problems if found in amounts greater than the health standard set by the United States Environmental Protection Agency (EPA). 1,1,1-Trichloroethane is used as a solvent and in pesticides, textile processing, cutting oil formulations, and printing inks. Synonyms: Methyl chloroform, 1,1,1-TCA . 1,1,1-Trichloroethane (1,1,1-TCA) is an organic liquid with a chloroform-like odor. 1,1,1-Trichloroethane (TCA) TABLE OF CONTENTS FIND OUT IF YOU YOU WORK WITH TRICHLOROETHANE HOW TCA CAN ENTER AND AFFECT YOUR BODY TESTS FOR EXPOSURE AND MEDICAL EFFECTS LEGAL EXPOSURE LIMITS REDUCING YOUR EXPOSURE RESOURCES Health Hazard Summary: 1,1,1-Trichloroethane (TCA) most commonly affects the nervous system, EPA Data Source: 1,1,1-Trichloroethane. To focus on inhibition acting directly on the reductive … Evaluation The no-observed-effect level for CNS effects of 1,1,1-trichloroethane in humans at rest has been estimated to be 350 ppm (equivalent to 2 100 mg/m3). Methyl chloroform (1,1,1-Trichloroethane) 71-55-6 Hazard Summary Methyl chloroform is used as a solvent and in many consumer products. It will react violently with dinitrogen tetraoxide, oxygen, liquid oxygen, sodium and sodium-potassium alloys. 1: 83-93. Reproductive Effects: Animal evidence suggests that 1,1,1-TCE does not cause reproductive effects. Mutagenicity: Evidence from studies using live animals suggests that 1,1,1-trichloroethane is not mutagenic. It will also react violently with acetone, zinc and nitrates. For humans at work the internal dose resulting from 350 ppm is not significantly different compared with humans at rest (Reitz, 1989, personal communication). Toxicological Summary for: 1,1,1-Trichloroethane . 1,1,1-Trichloroethane; CASRN 71-55-6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the . 1,1,1-Trichloroethane is rapidly taken up by humans after inhalation exposure. Environmental Health; 1,1,1-Trichloroethane; 1,1,1-Trichloroethane. IRIS assessment development process. Mixtures of chlorinated ethenes and ethanes are often found at contaminated sites. EPA Definitions: Cancer Health Effects Some people who drink water containing 1,1,1-trichloroethane well in excess of the maximum contaminant level (MCL) for many years could experience problems with their liver, nervous system, or circulatory system. JANET E. KESTER, PHD, DABT. It is largely used as a 1,1,1-Trichloroethane - Page 1 of 5. This includes aluminum, magnesium and their alloys. In this study, we undertook a systematic investigation of the inhibitory effects of 1,1,1-trichloroethane (1,1,1-TCA) and 1,1-dichloroethane (1,1-DCA) on chlorinated ethene dechlorination in three distinct Dehalococcoides-containing consortia. Effects reported in humans due to acute (short-term) inhalation exposure to methyl chloroform include hypotension, mild hepatic effects, and central nervous system (CNS) depression. Neurotoxicity: Some studies using sensitive neurobehavioural tests have shown altered scores for exposed workers. Risk assessment. April 10, 2018. Also known as: Methyl chloroform, 1,1,1-TCA Chemical reference number (CAS): 71-55-61.